HUMAN LEUKEMIA BONE MARROW LYSATE
Leukemia Sample
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Diagnosis: Acute myeloid leukemia
   
Sex: Male
Age: 35
     
Catalog Number:

Extraction 1, soluble protein fraction

T18-018-T-1

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T18-018-T-2

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:              Posterior iliac crest  
   
Hematology:

Leukocyte (WBC)

6.8 x 109 / L

 

Erythrocyte (RBC)

0.59 x 1012 / L

Lymphocyte

22%

 

Hemoglobin

2.4 g/dl

Neutrophil

45%

 

Hematocrit (PCV)

7 %

Eosinophil

 

 

Platelets

8 x 109 / L

Basophil

 

 

Blasts

24%

Monocyte

1%

 

 

 

Myelocytes

8%

 

 

 
   
Biochemistry:

LDH:

not done

 

Sodium (Na):

not done

Serum albumin:

not done

 

Potassium (K):

not done

Beta microglobulins:

not done

 

Chloride (Cl):

not done

Creatinin:

not done

 

Calcium (Ca):

not done

Creatinin clearance:

not done

 

Bicarbonate:

not done

Albuminuria:

not done

 

Glycemia:

not done
   
Microscopic appearance:

Hypochromic anisocytosis, macrocytosis.Erythropoiesis hypoplastic and normoblastic. Marrow shows effacement by blasts, abnormal promyelocytes with high N:C ratio, clumped nuclear chromatin, basophilic cytoplasm showing many agmophilic granules and Auer rods. Neutrophils and precursors show dysplastic feature—hypergranulation and hypolobulation. Cellularity about 75%. Residual hematopoiesis markedly suppressed along with interstitial infiltration with blasts. Reticulin Grade I. No evidence of granuloma or lymphoid aggregate seen.
   
Biological markers:

B cell marker:

 

T cell marker:

 

Other markers:

 

TdT:

 

Myeloperoxidase:

strongly positive in blasts

Nonspecific esterase:

 

Black Soudan:

 
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-26271

     
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