HUMAN LEUKEMIA BONE MARROW LYSATE
Leukemia Sample
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Diagnosis:

Precursor B-Cell acute lymphoblastic leukemia
   
Sex: Female
Age: 4
     
Catalog Number:

Extraction 1, soluble protein fraction

T18-008-T-1

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T18-008-T-2

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:             

Posterior iliac crest

  
   
Hematology:

Leukocyte (WBC)

2.14 x 109 / L

 

Erythrocyte (RBC)

3.63 x 1012 / L

Lymphocyte

85%

 

Hemoglobin

10.3 g/dl

Neutrophil

1%

 

Hematocrit (PCV)

33 %

Eosinophil

 

 

Platelets

23 x 109 / L

Basophil

 

 

Blasts

 

Monocyte

13%

 

 

 
   
Biochemistry:

LDH:

820 µU / L

 

Sodium (Na):

140 meq / L

Serum albumin:

not done

 

Potassium (K):

3.9 meq / L

Beta microglobulins:

not done

 

Chloride (Cl):

not done

Creatinin:

0.9 mg / dl

 

Calcium (Ca):

not done

Creatinin clearance:

not done

 

Bicarbonate:

24 meq / L

Albuminuria:

not done

 

Glycemia:

not done
   
Microscopic appearance: Normochromic anisocytosis, pancytopenia. Trilineage hematopoiesis markedly suppressed. The smear is diffusely populated with medium to small sized mononuclear cells with high N/C ratio, scanty granular cytoplasm, nucleus with irregular outline, coarse and clumped nuclear chromatin with inconspicuous nucleoli, cellularity 90% with reduced fat spaces. No evidence of granuloma or excessive fibrosis seen. Reticulin Grade I.
   
Biological markers:

B cell marker:

CD79a (+), CD34 (+), CD20 (+)

T cell marker:

CD10 (+)

Other markers:

 

TdT:

 

Myeloperoxidase:

Positive in blasts

Nonspecific esterase:

 

Black Soudan:

 
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-26457

     
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