HUMAN LEUKEMIA BONE MARROW LYSATE
Leukemia Sample
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Diagnosis: Precursor B-Cell acute lymphoblastic leukemia
   
Sex: Female
Age: 17
     
Catalog Number:

Extraction 1, soluble protein fraction

T18-006-T-1

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T18-006-T-2

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:              Posterior iliac crest  
   
Hematology:

Leukocyte (WBC)

18.06 x 109 / L

 

Erythrocyte (RBC)

1.4 x 1012 / L

Lymphocyte

 

 

Hemoglobin

3.8 g/dl

Neutrophil

 

 

Hematocrit (PCV)

12%

Eosinophil

 

 

Platelets

81 x 109 / L

Basophil

 

 

Blasts

 

Monocyte

 

 

 

 
   
Biochemistry:

LDH:

not done

 

Sodium (Na):

not done

Serum albumin:

not done

 

Potassium (K):

not done

Beta microglobulins:

not done

 

Chloride (Cl):

not done

Creatinin:

not done

 

Calcium (Ca):

not done

Creatinin clearance:

not done

 

Bicarbonate:

not done

Albuminuria:

not done

 

Glycemia:

not done
   
Microscopic appearance: Hypochromic anisocytosis, poikilo, polychromasia, pancytopenia. Cellularity >90%. Hematopoietic tissues are markedly suppressed. Marrow is diffusely infiltrated with blasts, which are small to medium sized. High N/C ratio. Scanty pale cytoplasm with regular cellular outlined open nuclear chromatin with inconspicuous nucleoli. No granuloma or excessive fibrosis seen. Reticulin grade 0.
   
Biological markers:

B cell marker:

CD79a (+)

T cell marker:

CD10 (+)

Other markers:

PAS block positive in blasts

TdT:

Positive

Myeloperoxidase:

Positive in blasts

Nonspecific esterase:

 

Black Soudan:

 
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-26436

     
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