HUMAN LEUKEMIA BONE MARROW LYSATE
Leukemia Sample
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Diagnosis: Acute lymphoblastic leukemia
   
Sex: Male
Age: 19
   
Catalog Number:

Extraction 1, soluble protein fraction

T18-002-T-1

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T18-002-T-2

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:              Posterior iliac crest  
   
Hematology:

Leukocyte (WBC)

2.29 x 1012 / L

 

Erythrocyte (RBC)

1.70 x 1012 / L

Lymphocyte

29%

 

Hemoglobin

4.3 g/dl

Neutrophil

71%

 

Hematocrit (PCV)

13%

Eosinophil

00%

 

Platelets

157 x 109 / L

Basophil

00%

 

Blasts

 

Monocyte

00%

 

 

 
   
Biochemistry:

LDH:

388 µU / L

 

Sodium (Na):

145 meq / L

Serum albumin:

not done

 

Potassium (K):

3.4 meq / L

Beta microglobulins:

not done

 

Chloride (Cl):

108 meq / L

Creatinin:

1.2 mg / dl

 

Calcium (Ca):

not done

Creatinin clearance:

not done

 

Bicarbonate:

24 meq / L

Albuminuria:

not done

 

 

 
   
Microscopic appearance: Hypochromic (+), Anisocytosis, crenated RBCs, blast cells seen. Cellularity is 90-100%, with complete effacement of normal hemopoiesis by blast cells. Precursor B Acute lymphoblastic leukemia, CALLA CD10 positive.
   
Biological markers:

B cell marker:

CD34 (+), CD20 (+), CD79a (+)

T cell marker:

CD3 (-), CD10 (+)

Other markers:

Lambda (+), Kappa light chain (-)

TdT:

 

Myeloperoxidase:

negative

Nonspecific esterase:

 

Black Soudan:

 
   
Comments:

CALLA positive precursor B-cell acute lymphoblastic leukemia
   
Immunohistochemistry: Myeloperoxidase negative.
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-22482

     
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