HUMAN KIDNEY TISSUE LYSATE

 Sample Kidney
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Diagnosis: Renal clear cell carcinoma
   
Sex: Male
Age: 45
Grade: 3
Stage: II  
Catalog Number:

Extraction 1, soluble protein fraction

T11-021-T-1

Human Kidney tumor tissue lysate

1 mg/ml, 100 µg/vial

T11-021-N-1

Human Kidney normal tissue lysate (matched)

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T11-021-T-2

Human Kidney tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:              Right Kidney.  
   
Gross Findings:

Tumor measures 8 cm in diameter, ill demarcated, moderately differentiated.

Cut section soft, white, and shows necrotic foci.
   
Microscopic findings: Sections show a proliferation of malignant tumor cells with large, round, irregular nuclei, and abundant cytoplasm. Nuclear chromatin is coarse with prominent nuclei. Mitotic figures are abundant. Many multinucleated cells are present. The tumor cells form clusters or sheets invading the stroma. The stroma is necrotic and infiltrated by numbers of lymphocytes, plasma cells, eosinophils, and neutrophils.
   
Histologic pattern:

Cell distribution:

+/-

 

Structure / Pattern:

+/-

Diffuse:

-

 

Streaming:

-

Mosaic:

+

 

Storiform:

-

Necrosis:

+

 

Fibrosis:

-

Lymphocytic infiltration:

-

 

Pallisading:

-

Vascular invasion:

+

 

Cystic degeneration:

-

Clusterized:

+

 

Bleeding:

+

Alveolar formation:

+

 

Myxoid change:

-

Indian file:

-

 

Psammoma body:

-
   
Cellular differentiation:

Squamous:

+/-

 

Adenomatous:

+/-

 

Sarcomatous:

+/-

Squamoid:

-

 

Glandular cell:

+

 

Round cell:

-

Spindle:

-

 

Cell stratification:

+

 

Spindle cell:

-

Keratin:

-

 

Secretion:

+

 

Leiomyoblast:

-

Desmosome:

-

 

Intracellular vacuole:

+

 

Lipoblast:

-

Pearl:

-

 

Glandular formation:

+

 

Rhadomyoblast:

-
   
Nuclear atypia:

Nuclear Appearance:

0

I

II

III

Anisonucleosis:

 

 

 

X

Hyperchromatism:

 

 

X

 

Nucleolar prominent:

 

 

X

 

Multinucleated giant cell:

 

 

 

X

Mitotic activity:

 

 

X

 

Nuclear grade:

 

 

X

 
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-10237

     
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