HUMAN KIDNEY TISSUE LYSATE


Diagnosis: Renal cell carcinoma
   
Sex: Female
Age: 44
Grade: 3
Stage: III, T3bN0Mx  
Catalog Number:

Extraction 1, soluble protein fraction

T11-009-T-1

Human Kidney tumor tissue lysate

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T11-009-T-2

Human Kidney tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

 
Location: Right Kidney.  
   
Gross findings:

Tumor size 10.4 cm.

Cut section, tan/yellow/red, hemorrhagic and necrotic.

Lymph nodes negative for metastatic carcinoma.

   
Microscopic findings: The tumor is composed of enlarged cells with oval-round nuclei, distinct nucleoli, and abundant amounts of clear or eosinophilic cytoplasm. Cellular pleomorphism is generally mild, however, in some areas severe anaplastic nuclear pleomorphism is seen. Cells are arranged in enlarged islands/nests with intervening fibrovascular septae. Extensive tumor necrosis is present. The neoplastic process does not extend through the renal capsule. Extension into the renal vein with involvement of the vascular margin of resection is seen. The non-neoplastic portion of kidney demonstrates varying degrees of glomerulosclerosis, interstitial fibrosis, and inflammation.
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-00355

     
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